![]() Or they may be fed a home-cooked diet, including vegetarian or boiled meat diets, which can also place them at a higher risk of taurine deficiency. However some cats may have taurine deficiency in relation to a certain disease and may require taurine added to their diets. For this reason, all cat foods are supplemented with taurine to avoid nutritional deficiency so that the condition is rare in regards to nutritional deprivation. Lack of this amino acid results in severe health repercussions, such as blindness and tooth decay, amongst other things. ![]() Taurine is one of these types of amino acids, and has been found to play an essential role in the diet of cats. They are critical to life, with over 20 types of amino acids present in the body.Įssential, or indispensable amino acids are a group of amino acids that cannot be synthesized in the body and are thus required to be taken in through diet. BMI, body mass index.Amino acids are building blocks for proteins and essential to the proper functioning of most of the body systems. A randomized controlled clinical trial in humans is warranted to assess the antiaging effects of taurine (bottom right). In humans, lower taurine concentrations were associated with multiple diseases (top right). Taurine supplementation affected several hallmarks of aging (middle). A reversal of this drop through taurine supplementation increased healthy life span in mice and worms but not in yeast (bottom left and top middle). DOI: 10.1126/science.abn9257 Taurine concentration in blood declines with aging (top left). From Parminder Singh et al., Taurine deficiency as a driver of aging. Hillblom Foundation Fellowship Victorian Cancer Agency (ECRF21036 and MCRF21002). This work was funded by core research grants from DBT-National Institute of Immunology a DBT Ramalingaswamy Fellowship the Nathan Shock Center of Excellence in the Basic Biology of Aging Project National Institutes of Health (R01HD107574, P30AG013280, T32AG066574) Wellcome (098051) Deutsche Forschungsgemeinschaft (450149205-TRR333/1) Institut National Du Cancer (PLBIO21-228 ) Science and Engineering Research Board (STR/2019/00064) Department of Biotechnology (BT/PR40325/BTIS/1) a Longevity Impetus Grant Academy of Finland Center of Excellence in Complex Disease Genetics (312074, 336824, and 352793) The Sigrid Juselius Foundation a Larry L. Parminder Singh, Kishore Gollapalli, Stefano Mangiola, Daniela Schranner, Mohd Aslam Yusuf, Manish Chamoli et al., Taurine deficiency as a driver of aging. However, a randomized clinical trial would be necessary to determine if taurine supplementation improves health in humans. These evidences in humans suggest that taurine deficiency may be a driver of aging in humans as well. Moreover, taurine levels increased with a bout of exercise, which is known to improve many aging related variables. In humans, the group showed that low levels of taurine in aged humans was associated with disorders like obesity, hypertension, inflammation, and diabetes. ![]() At a cellular level, taurine reduced the hallmarks of aging–reduced senescence, suppressed consequences of telomerase deficiency, mitochondrial dysfunction, DNA damage, and inflammation. Similar health effects were reported in rhesus monkeys. Taurine-fed mice were also healthier than the untreated mice with improved bone and muscle strength, memory, and immune function. ![]() In Caenorhabditis elegans, taurine supplementation increased the average life span by 10 to 23%. In taurine-fed mice, the average life span increased by 10 to 12%. This observation led the group to check the effect of taurine supplementation on health span and life span in several species. The group found taurine abundance decreases substantially with age in the bloodstream of mice, monkeys, and humans. Yadav from Columbia University and involving the National Institute of Immunology and other institutes – now shows the deficiency of taurine to be a driver of aging. However, how taurine affects aging is unknown.Ī multi-national, collaborative study– led by Dr Vijay K. Studies have shown an association of taurine in blood with health and its decline in some tissues with age. Taurine’s function in the body is implicated in muscle and bone development, immune function, and neurological functions–processes that decline with age. Taurine is a semi-essential amino acid made within our body and is also obtained from an animal-based diet. Taurine deficiency may be a driver of aging in animals
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